The Untold Truth Of Futurama

"Futurama" was always meant to be a comedy, but some episodes would occasionally touch on Fry's sadness and loss at being stuck in the future, having left his life and loved ones behind. The 2002 episode "Jurassic Bark" is one of those episodes. 

While visiting a museum, Fry discovers the fossilized remains of his 20th century dog, Seymour. Professor Farnsworth tells Fry that he could feasibly take some of Seymour's DNA and create a clone. During the cloning process, Fry learns that Seymour lived to be 15. He figures that after he'd disappeared in 1999, Seymour must have lived a long, happy life without him. And then, the saddest flashback ever flashed across TV screens: Seymour didn't move on — he waited for Fry outside the pizzeria where he used to work for more than a decade. The episode ends with Seymour closing his eyes, passing away, and everyone watching in tears. 

Amazingly, this episode could have been even sadder. As revealed in the episode's DVD commentary, the writers' toyed around with Fry finding the remains of his mother, and then considering, but ultimately dismissing, cloning her.