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| 15 Nov 2023 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Sale | 19 | $369.92 | $7,028 15 Nov 2023 | 32,038 | ↗ |
| 9 Aug 2023 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Sale | 63 | $345.51 | $21,767 9 Aug 2023 | 32,038 | ↗ |
| 24 Feb 2023 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Sale | 4,238 | $287.51 | $1,218,467 24 Feb 2023 | 32,038 | ↗ |
| 17 Feb 2023 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Sale | 4,002 | $293.77 | $1,175,668 17 Feb 2023 | 40,246 | ↗ |
| 14 Feb 2023 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Sale | 6,398 | $298.70 | $1,911,083 14 Feb 2023 | 47,998 | ↗ |
| 10 Feb 2023 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Sale | 4,798 | $298.90 | $1,434,122 10 Feb 2023 | 54,396 | ↗ |
| 6 Feb 2023 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Option | 1,304 | $187.53 | $244,539 6 Feb 2023 | 69,949 | ↗ |
| 15 Nov 2022 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Sale | 34 | $308.61 | $10,493 15 Nov 2022 | 36,077 | ↗ |
| 7 Nov 2022 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Option | 1,303 | $187.53 | $244,352 7 Nov 2022 | 37,380 | ↗ |
| 8 Aug 2022 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Option | 1,304 | $187.53 | $244,539 8 Aug 2022 | 37,381 | ↗ |
| 19 Jul 2022 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Sale | 17,865 | $288.65 | $5,156,732 19 Jul 2022 | 36,077 | ↗ |
| 24 Feb 2022 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Sale | 7,572 | $230.98 | $1,748,981 24 Feb 2022 | 36,077 | ↗ |
| 17 Feb 2022 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Sale | 4,312 | $230.97 | $995,943 17 Feb 2022 | 49,687 | ↗ |
| 14 Feb 2022 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Sale | 2,444 | $232.02 | $567,057 14 Feb 2022 | 57,438 | ↗ |
| 10 Feb 2022 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Sale | 2,297 | $235.02 | $539,841 10 Feb 2022 | 59,882 | ↗ |
| 1 Feb 2022 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Option | 4,660 | $86.52 | $403,183 1 Feb 2022 | 70,357 | ↗ |
| 15 Nov 2021 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Sale | 34 | $187.22 | $6,365 15 Nov 2021 | 33,589 | ↗ |
| 17 May 2021 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Sale | 79 | $216.36 | $17,092 17 May 2021 | 33,589 | ↗ |
| 24 Feb 2021 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Sale | 3,028 | $213.39 | $646,145 24 Feb 2021 | 33,589 | ↗ |
| 17 Feb 2021 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Sale | 7,825 | $211.83 | $1,657,570 17 Feb 2021 | 39,033 | ↗ |
| 11 Feb 2021 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Sale | 5,283 | $210.54 | $1,112,283 11 Feb 2021 | 53,098 | ↗ |
| 16 Nov 2020 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Sale | 38 | $223.47 | $8,492 16 Nov 2020 | 28,902 | ↗ |
| 6 Aug 2020 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Option | 1,223 | $155.57 | $190,262 6 Aug 2020 | 30,125 | ↗ |
| 3 Aug 2020 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Option | 2,330 | $86.52 | $201,592 3 Aug 2020 | 31,232 | ↗ |
| 15 May 2020 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Sale | 82 | $284.37 | $23,318 15 May 2020 | 28,902 | ↗ |
| 12 May 2020 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Option | 1,304 | $187.53 | $244,539 12 May 2020 | 30,206 | ↗ |
| 6 May 2020 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Option | 1,222 | $155.57 | $190,107 6 May 2020 | 30,124 | ↗ |
| 4 May 2020 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Option | 2,330 | $86.52 | $201,592 4 May 2020 | 31,232 | ↗ |
| 24 Feb 2020 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Sale | 3,028 | $233.41 | $706,765 24 Feb 2020 | 28,902 | ↗ |
| 17 Feb 2020 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Sale | 3,128 | $243.67 | $762,200 17 Feb 2020 | 34,346 | ↗ |
| 10 Feb 2020 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Sale | 17,032 | $246.11 | $4,191,746 10 Feb 2020 | 39,970 | ↗ |
| 5 Feb 2020 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Option | 2,526 | $172.06 | $434,624 5 Feb 2020 | 72,836 | ↗ |
| 3 Feb 2020 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Option | 4,126 | $88.49 | $365,110 3 Feb 2020 | 35,679 | ↗ |
| 25 Nov 2019 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Option | 3,910 | $187.53 | $733,242 25 Nov 2019 | 35,463 | ↗ |
| 15 Nov 2019 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Sale | 60 | $205.95 | $12,357 15 Nov 2019 | 31,553 | ↗ |
| 6 Nov 2019 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Option | 1,223 | $155.57 | $190,262 6 Nov 2019 | 32,776 | ↗ |
| 4 Nov 2019 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Option | 4,126 | $88.49 | $365,110 4 Nov 2019 | 35,679 | ↗ |
| 22 Oct 2019 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Option | 3,669 | $155.57 | $570,786 22 Oct 2019 | 35,222 | ↗ |
| 19 Aug 2019 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Option | 12,501 | $103.25 | $1,290,728 19 Aug 2019 | 36,212 | ↗ |
| 15 May 2019 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Sale | 91 | $165.41 | $15,052 15 May 2019 | 31,553 | ↗ |
| 19 Feb 2019 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Sale | 5,624 | $187.00 | $1,051,688 19 Feb 2019 | 31,553 | ↗ |
| 11 Feb 2019 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Sale | 32,956 | $180.22 | $5,939,330 11 Feb 2019 | 37,177 | ↗ |
| 4 Feb 2019 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Option | 4,126 | $88.49 | $365,110 4 Feb 2019 | 41,443 | ↗ |
| 22 Jan 2019 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Option | 2,125 | $131.89 | $280,266 22 Jan 2019 | 41,238 | ↗ |
| 18 Jan 2019 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Option | 1,223 | $155.70 | $190,421 18 Jan 2019 | 40,336 | ↗ |
| 15 Nov 2018 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Sale | 100 | $163.75 | $16,375 15 Nov 2018 | 39,113 | ↗ |
| 7 Nov 2018 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Option | 2,125 | $131.89 | $280,266 7 Nov 2018 | 41,238 | ↗ |
| 2 Nov 2018 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Option | 4,126 | $88.49 | $365,110 2 Nov 2018 | 41,443 | ↗ |
| 1 Oct 2018 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Option | 2,445 | $155.57 | $380,369 1 Oct 2018 | 41,558 | ↗ |
| 28 Aug 2018 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Option | 2,125 | $131.89 | $280,266 28 Aug 2018 | 41,238 | ↗ |
| 2 Aug 2018 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Option | 4,126 | $88.49 | $365,110 2 Aug 2018 | 41,443 | ↗ |
| 16 Jul 2018 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Option | 23,375 | $131.89 | $3,082,929 16 Jul 2018 | 62,488 | ↗ |
| 29 Jun 2018 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Sale | 44,331 | $164.98 | $7,313,728 29 Jun 2018 | 39,113 | ↗ |
| 15 May 2018 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Sale | 98 | $155.78 | $15,266 15 May 2018 | 69,999 | ↗ |
| 12 Feb 2018 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Sale | 6,403 | $150.82 | $965,700 12 Feb 2018 | 69,999 | ↗ |
| 2 Feb 2018 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Option | 1,796 | $91.05 | $163,526 2 Feb 2018 | 51,557 | ↗ |
| 22 Jan 2018 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Option | 1,796 | $91.05 | $163,526 22 Jan 2018 | 51,557 | ↗ |
| 16 Jan 2018 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Sale | 56,250 | $156.99 | $8,830,688 16 Jan 2018 | 49,761 | ↗ |
| 15 Nov 2017 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Sale | 306 | $149.12 | $45,631 15 Nov 2017 | 106,011 | ↗ |
| 31 Aug 2017 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Option | 1,796 | $91.05 | $163,526 31 Aug 2017 | 107,807 | ↗ |
| 19 Jul 2017 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Option | 28,979 | $84.49 | $2,448,436 19 Jul 2017 | 134,990 | ↗ |
| 5 Jun 2017 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Option | 7,500 | $72.14 | $541,050 5 Jun 2017 | 113,511 | ↗ |
| 15 May 2017 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Sale | 181 | $114.37 | $20,701 15 May 2017 | 106,011 | ↗ |
| 28 Apr 2017 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Option | 7,500 | $63.14 | $473,550 28 Apr 2017 | 113,511 | ↗ |
| 13 Feb 2017 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Sale | 6,403 | $87.68 | $561,415 13 Feb 2017 | 106,011 | ↗ |
| 13 Feb 2017 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Sale | 6,403 | $87.68 | $561,415 13 Feb 2017 | 106,011 | ↗ |
| 1 Dec 2015 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Option | 5,000 | $72.14 | $360,700 1 Dec 2015 | 80,000 | ↗ |
| 18 Nov 2015 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Option | 15,000 | $67.64 | $1,014,600 18 Nov 2015 | 90,000 | ↗ |
| 28 Nov 2014 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Option | 3,500 | $60.58 | $212,030 28 Nov 2014 | 3,500 | ↗ |
| 28 Oct 2014 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Option | 2,000 | $63.14 | $126,280 28 Oct 2014 | 2,000 | ↗ |
| 6 Oct 2014 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Option | 1,405 | $63.14 | $88,712 6 Oct 2014 | 1,405 | ↗ |
| 1 Oct 2014 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Option | 10,595 | $63.14 | $668,968 1 Oct 2014 | 10,595 | ↗ |
| 29 Sep 2014 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Option | 2,500 | $59.55 | $148,875 29 Sep 2014 | 2,500 | ↗ |
| 24 Sep 2014 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Option | 2,500 | $59.55 | $148,875 24 Sep 2014 | 2,500 | ↗ |
| 19 Sep 2014 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Option | 5,000 | $59.55 | $297,750 19 Sep 2014 | 5,000 | ↗ |
| 5 Sep 2014 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Option | 2,500 | $59.55 | $148,875 5 Sep 2014 | 2,500 | ↗ |
| 31 Jul 2014 | VRTXVertex Pharmaceuticals, Inc. | David Altshuler EVP, Global Research, and CSO | Option | 5,000 | $59.55 | $297,750 31 Jul 2014 | 5,000 | ↗ |
